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| Field | Last updated |
|---|---|
| Aliases | Regular human insulin, Humulin R, Novolin R, Insulin lispro, Insulin glargine |
| Category | Metabolic |
| Formula | C₂₅₇H₃₈₃N₆₅O₇₇S₆ |
| Molecular weight | 5807.6 Da |
| Half-life | ~5 min (IV regular); ~2 hours (SC regular) |
| Mechanism (summary) | "Insulin" is a drug class, not one marketed compound. There are multiple human insulins and engineered analogs, with formulation-specific kinetics, dosing, and storage rules. The hormone is essential for survival in type 1 diabetes and a core escalation step in type 2 diabetes. Representative regular human insulin labels (Humulin R, Novolin R) anchor the safety and pharmacology summary here. |
| Dosing notes | Dosing is inherently individualized. Type 1 diabetes typically totals 0.4–1.0 units/kg/day across basal and prandial components. Type 2 diabetes basal often starts at 10 units/day or 0.1–0.2 units/kg/day. Regular human insulin (Humulin R) is dosed 30 minutes before eating; intravenous regular insulin is restricted to monitored clinical settings. Always defer to the specific formulation label. |
| Storage | Storage is brand- and formulation-specific. Humulin R vials are protected from heat and light, not frozen, and held at room temperature for a total of 31 days once opened. Novolin R allows unopened refrigerated storage until expiration or room-temperature storage up to 42 days; opened vials are kept at room temperature and discarded after 42 days. Other insulins (analogs, mixed, pens) have their own storage rules — always check the specific label. |
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| Read more | Full reference → |
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