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| Field | Last updated |
|---|---|
| Aliases | Lys-Pro-Val, alpha-MSH (11-13), K-P-V tripeptide |
| Category | Immune Modulation |
| Formula | C₁₆H₃₀N₄O₄ |
| Molecular weight | 342.44 Da |
| Half-life | ~few minutes |
| Mechanism (summary) | KPV is the tripeptide Lys-Pro-Val, a minimal active fragment from the C-terminus of alpha-MSH. It is one of the more interesting translational anti-inflammatory peptides in gastrointestinal research, but current evidence is overwhelmingly preclinical. |
| Dosing notes | Routes vary considerably across papers, including drinking-water oral exposure, oral nanoparticle delivery, and intracolonic administration. One commonly cited DSS-colitis study identified about 10 mcg/day as an effective daily amount in mice. Because administration platforms differ so much, cross-study dose comparison is difficult. |
| Storage | No reliable compound-specific storage or shelf-life source was retrieved from official labels or manufacturer datasheets in the reviewed set. |
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| Read more | Full reference → |
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