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| Field | Last updated |
|---|---|
| Aliases | Mechano-Growth Factor, IGF-1Ec, MGF E-domain peptide, IGF-1 splice variant |
| Category | Healing & Repair |
| Formula | — |
| Molecular weight | 2867.27 Da |
| Half-life | ~few minutes (highly labile) |
| Mechanism (summary) | "Mechano-Growth Factor" usually refers to the IGF-1Ec splice variant or, in many peptide products, to synthetic peptides derived from the MGF E-domain. MGF expression rises after mechanical loading, stretch, or injury, but the field has been marked by disputed interpretations and confirmation-bias concerns. |
| Dosing notes | Human dosing has not been standardized. There is no FDA-approved MGF drug product. Anti-doping authorities prohibit MGF. |
| Storage |
No product-specific, peer-reviewed storage standard for synthetic MGF peptides was located. Lab default: lyophilized storage at -20°C or below, protection from moisture and light, aliquoting after reconstitution to avoid repeated freeze-thaw. |
| Read more | Full reference → |
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