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| Field | Last updated |
|---|---|
| Aliases | Mitochondrial open reading frame of the 12S rRNA-c, MOTS-c peptide, Mitochondrial-derived peptide (MDP), Exercise-responsive metabolic peptide |
| Category | Metabolic |
| Formula | C₁₀₂H₁₅₇N₂₉O₂₂S₂ |
| Molecular weight | 2174.61 Da |
| Half-life | ~9 hours |
| Mechanism (summary) | MOTS-c is a mitochondrial-derived peptide, not a conventional secretagogue or growth factor. Encoded within mitochondrial 12S rRNA, it has become a major research focus in metabolism, exercise biology, and healthy aging. In animals it behaves like an exercise-responsive metabolic regulator. |
| Dosing notes | No established human dosing standard exists. FDA states it has not identified human exposure data on compounded MOTS-c products. An interventional human trial is registered but has not yielded a clinical regimen. |
| Storage | No validated product-specific MOTS-c storage standard located. Research peptide baseline: cold lyophilized storage (typically -20°C or colder), light protection, dryness, and minimal freeze-thaw after reconstitution. |
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| Read more | Full reference → |
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