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Compare peptides · AminoCatalog

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Semax

Field	Semax × Last updated 2 months ago
Aliases	Semaks, Met-Glu-His-Phe-Pro-Gly-Pro, ACTH(4-7) Pro-Gly-Pro analog, Semax 0.1% nasal drops, Semax 1% nasal drops
Category	Cognitive & Nootropic
Formula	C₃₇H₅₁N₉O₁₀S
Molecular weight	813.94 Da
Half-life	~20–30 min (intranasal)
Mechanism (summary)	Semax is a synthetic heptapeptide (Met-Glu-His-Phe-Pro-Gly-Pro) — an analog of an ACTH fragment, but devoid of hormonal activity. Marketed in Russia as a 0.1% (general use) and 1% (stroke) intranasal drop. Used for neuroprotection, stroke recovery, cognitive disorders, optic-nerve disease, and adaptation under stress.
Dosing notes	0.1% nasal drops: 50 mcg per drop; typical cerebrovascular and cognitive regimens 800–8000 mcg/day for 10–14 days. 1% stroke dosing: 6–12 mg/day for moderate stroke and 12–20 mg/day for severe stroke, typically for 10 days.