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| Field | Last updated |
|---|---|
| Aliases | Tα1, Thymalfasin, Zadaxin, synthetic Thymosin Alpha-1 |
| Category | Immune Modulation |
| Formula | C₁₂₉H₂₁₅N₃₃O₅₅ |
| Molecular weight | 3108.27 Da |
| Half-life | ~2 hours |
| Mechanism (summary) | Thymosin alpha-1 (thymalfasin / Zadaxin) is a synthetic 28-amino-acid peptide identical to the endogenous form. International monographs describe use in chronic hepatitis B and as an immunomodulator. It is NOT FDA-approved — the FDA's 2024 compounding briefing explicitly states no Tα1 drug products are approved in the U.S. |
| Dosing notes | Per monograph (chronic hepatitis B): 1.6 mg subcutaneously twice weekly, with doses separated by 3 or 4 days, for 6 months. In the U.S. these are NOT FDA-approved dosing standards because no Tα1 product is FDA-approved. |
| Storage |
Per Zadaxin monograph: store at 2–8 °C and use immediately after reconstitution. |
| Read more | Full reference → |
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