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Editorial entries for every peptide we cover — each page links the vendors that carry it, the reviews users have left, and the literature behind it.
Dihexa is a synthetic angiotensin IV (AngIV) analogue reported to be orally active and able to penetrate the blood-brain barrier. The accessed literature does not provide evidence of approved human use and does not identify a human clinical development dataset; evidence status is therefore best described as preclinical.
In research catalogs, this compound is usually called N-Acetyl Semax amidate — a modified version of Semax (an ACTH(4-10)-derived heptapeptide). PubChem identifies the modified molecule, but indexed clinical evidence for the modified form is limited. Most meaningful biological and clinical discussion still comes from the parent peptide Semax.
Pinealon is the EDR tripeptide (Glu-Asp-Arg), a Khavinson-school neuroregulatory bioregulator. Russian references list it as a dietary supplement rather than a prescription medicinal product, and it has no FDA or EMA drug approval.
Semax is a synthetic heptapeptide (Met-Glu-His-Phe-Pro-Gly-Pro) — an analog of an ACTH fragment, but devoid of hormonal activity. Marketed in Russia as a 0.1% (general use) and 1% (stroke) intranasal drop. Used for neuroprotection, stroke recovery, cognitive disorders, optic-nerve disease, and adaptation under stress.